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- Clarhed, Ulrika, et al.
(author)
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BMI as a risk factor for the development of chronic rhinosinusitis: a prospective population-based study
- 2022
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In: European Archives of Oto-Rhino-Laryngology. - : Springer Science and Business Media LLC. - 0937-4477 .- 1434-4726. ; 279
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Journal article (peer-reviewed)abstract
- Purpose Obesity is a growing, global health problem and previous cross-sectional studies have demonstrated an association between obesity and chronic rhinosinusitis (CRS). There is, however, a lack of prospective studies regarding the impact of obesity on developing (new-onset) CRS. Methods Questionnaire-based data (n = 5769) relating to new-onset CRS and Body Mass Index (BMI) were collected in 2013 and 2018 from the Telemark population study in Telemark, Norway. Odds ratios for the risk of new-onset CRS in 2018 in relation to BMI in 2013 were calculated, adjusted for smoking habits, asthma, gender and age. Results When comparing the group with normal weight (18.5 <= BMI < 25) with the obese group (BMI >= 30), the odds of new-onset CRS was 53% higher [OR 1.53 (1.11, 2.10)] in the obese group. Conclusion CRS is a multifactorial disease with different phenotypes and it is important to consider obesity when assessing patients with CRS in a clinical setting.
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| 2. |
- Clarhed, Ulrika, et al.
(author)
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Chronic Rhinosinusitis Related to Occupational Exposure- the Telemark Population Study.
- 2018
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In: Journal of occupational and environmental medicine. - 1536-5948. ; 60:7
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Journal article (peer-reviewed)abstract
- To investigate the association between occupational exposure and chronic rhinosinusitis.A random population from the region of Telemark, aged 16-50, answered a respiratory questionnaire including questions on chronic rhinosinusitis and exposure in the occupational environment.A total of 16,099/48,142 subjects responded. The prevalence of chronic rhinosinusitis was 9%. Exposure associated with chronic rhinosinusitis comprised paper dust (OR 1.3, 95% CI 1.1, 1.5), cleaning agents (OR 1.2, CI 1.0, 1.3), metal dust (OR 1.3, CI 1.1, 1.6), animals (OR 1.2, CI 1.0, 1.5), moisture/mould/mildew (OR 1.3, CI 1.1, 1.5) and physically strenuous work (OR 1.4, CI 1.2, 1.7).Occupational exposure to paper dust, cleaning agents, metal dust, animals, moisture/mould/mildew and physically strenuous work was independently related to having chronic rhinosinusitis. An occupational history should be reviewed when assessing patients with chronic rhinosinusitis.
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